Treatment Options for Neuroblastoma
Treatment of low-risk neuroblastoma may include the following:
Treatment of intermediate-risk neuroblastoma may include the following:
Treatment of high-risk neuroblastoma may include the following:
- A regimen of combination chemotherapy, surgery, stem cell rescue, radiation therapy, and anti-GD2 ch14.18 with interleukin-2 (IL-2), granulocyte-macrophage colony-stimulating factor (GM-CSF), and isotretinoin.
- A clinical trial of combination chemotherapy and stem cell rescue following chemotherapy.
- A clinical trial of chemotherapy combined with mIBG, followed by surgery, more chemotherapy, stem cell rescues, radiation therapy, and isotretinoin.
- A clinical trial of chemotherapy and stem cell rescue followed by isotretinoin with or without monoclonal antibody therapy and biologic therapy.
Stage 4S Neuroblastoma
Patients First Treated for Low-Risk Neuroblastoma
Treatment for recurrent neuroblastoma that has spread to other parts of the body may include the following:
- Observation for certain infants.
- Surgery followed by chemotherapy.
- Combination chemotherapy.
Patients First Treated for Intermediate-Risk Neuroblastoma
Recurrent neuroblastoma that has spread to other parts of the body is treated the same way as newly diagnosed high-risk neuroblastoma.
Patients First Treated for High-Risk Neuroblastoma
Because there is no standard treatment for recurrent neuroblastoma in patients first treated for high-risk neuroblastoma, patients may want to consider a clinical trial. For information about clinical trials, please see the NCI Web site.
Patients with Recurrent CNS Neuroblastoma
Treatments in Clinical Trials for Progressive/Recurrent Neuroblastoma
Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with neuroblastoma. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. Talk with your child's doctor about clinical trials that may be right for your child. General information about clinical trials is available from the NCI Web site.