National Cryo-Electron Microscopy Facility Team Members

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The National Cryo-EM Facility (NCEF) consists of a core team that provides cryo-EM services to cancer researchers.  The Frederick National Lab Advisory Committee and an ad hoc NCEF working group provides strategic oversight and recommendations to the core team.

National Cryo-EM Team

Ulrich Baxa, Ph.D.
NCEF Senior Microscopist

Ulrich Baxa earned his Ph.D. in Physical Biochemistry, and has research expertise in Biochemistry, Biophysics, and Structural Biology. He has worked in cryo-EM laboratories for many years and has a strong background in structural analysis by electron microscopy and high resolution cryo-electron microscopy imaging.


 
Thomas Edwards, Ph.D.
NCEF Microscopist

Thomas Edwards earned his Ph.D. in Molecular Virology focusing on structural studies of intra-cellular virus induced membranes formed during infection by alphaviruses and flaviviruses. In addition to virology, Thomas has expertise in electron tomography and single particle cryo-EM.


 
Helen Wang, MBA, PMP
NCEF Scientific Project Manager

Helen Wang earned her MBA with a focus in Project Management and holds a PMP certification. She has worked in academic research in Pharmacology, Physiology and Biophysics. In addition, she has worked in Infectious Disease research in government labs, and has private industry experience in Project Management on government contract projects.


 
Sriram Subramaniam, Ph.D.
NCEF Scientific Advisor
High Resolution Electron Microscopy Research Program

Sriram Subramaniam, the founding Director of NCEF, now serves as its Scientific Advisor. He is currently Senior Investigator and Chief of the Biophysics Section in the Laboratory of Cell Biology, Center for Cancer Research, NCI, with adjunct faculty appointments at The Johns Hopkins University School of Medicine and the Institute for Advanced Computer Studies at the University of Maryland, College Park.


 

NCEF Advisory Group

Frederick National Lab Advisory Committee (FNLAC) reviews the state of research at the FNLCR and makes recommendations for the best use of its capabilities and infrastructure.

Ad Hoc NCEF Working Group

An ad hoc advisory committee composed of members of the cryo-EM and structural biology communities provides advice to the NCI on operational aspects of the facility. The advisory committee members are listed below.

Ad Hoc NCEF Working Group Chair

Steven J. Ludtke, Ph.D.
Professor, Department of Biochemistry and Molecular Biology
Co-Director, National Center for Macromolecular Imaging, Center for Computational and Integrative Biomedical Research
Baylor College of Medicine
Houston, Texas

Ad Hoc NCEF Working Group Members

L. Mario Amzel, Ph.D.
Professor, Director, Department of Biophysics and Biophysical Chemistry
The Johns Hopkins University School of Medicine
Baltimore, Maryland

Edward H. Egelman, Ph.D.
Professor, Department of Biochemistry and Molecular Genetics
University of Virginia School of Medicine
Charlottesville, Virginia

Angela M. Gronenborn, Ph.D.
UPMC Rosalind Franklin Professor and Chair, Department of Structural Biology
Professor, Department of Bioengineering, Swanson School of Engineering
Director, Pittsburgh Center for HIV Protein Interactions
University of Pittsburgh
Pittsburgh, Pennsylvania

Stephen C. Harrison, Ph.D.
Giovanni Armenise-Harvard Professor of Basic Medical Sciences, Department of Biological Chemistry and Molecular Pharmacology
Director, Center for Molecular and Cellular Dynamics, Investigator, Howard Hughes Medical Institute
Harvard Medical School
Boston, Massachusetts

Grant J. Jensen, Ph.D.
Professor of Biophysics and Biology, Division of Biology and Biological Engineering
Investigator, Howard Hughes Medical Institute
California Institute of Technology
Pasadena, California

Piermaria J. Oddone, Ph.D.
Director Emeritus
Fermi National Accelerator Laboratory
Healdsburg, California

Z. Hong Zhou, Ph.D.
Director, Electron Imaging Center for NanoMachines
Professor, Department of Microbiology, Immunology and Molecular Genetics
Member, California NanoSystems Institute
University of California, Los Angeles
Los Angeles, California

Executive Secretary

Sara Hook, Ph.D.
NCEF Program Officer
National Cancer Institute
National Institutes of Health
Bethesda, Maryland

  • Posted: October 13, 2017

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