Prevention Clinical Trials for Melanoma

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Clinical trials are research studies that involve people. The clinical trials on this list are for melanoma prevention. All trials on the list are supported by NCI.

NCI’s basic information about clinical trials explains the types and phases of trials and how they are carried out. Clinical trials look at new ways to prevent, detect, or treat disease. You may want to think about taking part in a clinical trial. Talk to your doctor for help in deciding if one is right for you.

Trials 1-3 of 3
  • Effects of Solar Simulated Light Exposure on Skin Samples from Patients with Metastatic Cancers Treated with Target Therapies

    This pilot clinical trial studies the effects of solar (sun) simulated light exposure on skin sample from patients with melanoma, colon cancer, liver cancer, or thyroid cancer that has spread to other parts of the body (metastatic) treated with target therapies. Therapies known as Raf, mitogen-activated protein kinase kinase (MEK), or protein kinase inhibitors (target therapies) may cause skin side effects such as moles also called melanocytic nevus. Studying the effects of Raf inhibition when given with MEK or protein kinase inhibitors on skin samples before and after solar simulated light exposure may help doctors evaluate changes which occur in the skin of patients undergoing metastatic cancer treatment with Raf.
    Location: The University of Arizona Medical Center-University Campus, Tucson, Arizona

  • Family-Focused Behavioral Intervention in Improving Adherence to Melanoma Prevention in High-Risk Children

    This pilot clinical trial studies how well a family-focused behavioral intervention works in improving adherence to melanoma prevention in children with a family history of melanoma. Educating children and parents / caregivers together about ways to prevent melanoma and creating a family skin protection plan may help children learn new skills and strategies to practice melanoma preventive behaviors.
    Location: Huntsman Cancer Institute / University of Utah, Salt Lake City, Utah

  • Sulforaphane in Treating Patients With Atypical Nevi Previously Diagnosed With Melanoma

    This pilot clinical trial studies sulforaphane in treating patients with atypical nevi previously diagnosed with melanoma. Chemoprevention is the use of certain drugs to keep cancer from forming. The use of sulforaphane may keep cancer from forming in melanoma.
    Location: University of Pittsburgh Cancer Institute (UPCI), Pittsburgh, Pennsylvania