Clinical Trials Using Clarithromycin
Clinical trials are research studies that involve people. The clinical trials on this list are studying Clarithromycin. All trials on the list are supported by NCI.
NCI’s basic information about clinical trials explains the types and phases of trials and how they are carried out. Clinical trials look at new ways to prevent, detect, or treat disease. You may want to think about taking part in a clinical trial. Talk to your doctor for help in deciding if one is right for you.
Ixazomib Citrate with Pomalidomide, Clarithromycin and Dexamethasone in Treating Patients with Relapse or Refractory Multiple Myeloma
This phase I / II trial studies the side effects and best dose of clarithromycin when given together with ixazomib citrate, pomalidomide, and dexamethasone and to see how well it works in treating patients with multiple myeloma that has come back or does not respond to treatment. Biological therapies, such as clarithromycin, pomalidomide, and dexamethasone, use substances made from living organisms that may stimulate the immune system in different ways and stop cancer cells from growing. Ixazomib citrate may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Giving clarithromycin with ixazomib citrate, pomalidomide and dexamethasone may be a better treatment for patients with multiple myeloma.
Location: 3 locations
Docetaxel or Cabazitaxel with Clarithromycin in Treating Patients with Metastatic Castration-Resistant Prostate Cancer
This phase Ib trial studies the side effects and best dose of docetaxel or cabazitaxel when given together with clarithromycin in treating patients with castration-resistant prostate cancer that has spread to other places in the body. Drugs used in chemotherapy, such as docetaxel and cabazitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Clarithromycin may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Giving docetaxel or cabazitaxel with clarithromycin may work better in treating patients with castration-resistant prostate cancer.
Location: Johns Hopkins University / Sidney Kimmel Cancer Center, Baltimore, Maryland
BiRd vs. Rd as Initial Therapy in Multiple Myeloma
This is a randomized, open-label, phase III study to investigate the efficacy of combination therapy with an induction phase utilizing a combination clarithromycin (Biaxin®), lenalidomide (Revlimid®), dexamethasone (Decadron®), in multiple myeloma patients who are newly diagnosed and require treatment when compared to patients who receive lenalidomide and dexamethasone alone.
Location: University of Colorado Hospital, Aurora, Colorado