Clinical Trials Using Curcumin

Clinical trials are research studies that involve people. The clinical trials on this list are studying Curcumin. All trials on the list are supported by NCI.

NCI’s basic information about clinical trials explains the types and phases of trials and how they are carried out. Clinical trials look at new ways to prevent, detect, or treat disease. You may want to think about taking part in a clinical trial. Talk to your doctor for help in deciding if one is right for you.

Trials 1-5 of 5
  • Curcumin in Treating HIV Infected and Uninfected Women with High Grade Cervical Squamous Intraepithelial Neoplasia

    This randomized phase II trial studies how well curcumin works in treating human immunodeficiency virus (HIV) infected and uninfected women with high grade cervical squamous intraepithelial neoplasia. Natural or herbal treatments, such as curcumin, may help slow down destroy, or prevent the growth of precancerous cells.
    Location: 2 locations

  • Curcumin in Treating Patients with Prostate Cancer That Was Removed by Surgery

    This randomized phase II trial studies curcumin compared to placebo in treating patients with prostate cancer that was removed by surgery. Curcumin may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and may help to decrease or prevent prostate cancer from returning after surgery.
    Location: UT Southwestern / Simmons Cancer Center-Dallas, Dallas, Texas

  • Curcumin and Ursolic Acid for the Treatment of Prostate Cancer

    This phase I trial investigates the side effects of curcumin and ursolic acid, as well as their rate of absorption in the blood (bioavailability), their absorption in the prostate, and their interactions and effect within the body in patients with prostate cancer. Dietary supplements, such as curcumin and ursolic acid, may slow the growth of prostate cancer. This trial may help researchers learn if a combination of curcumin and ursolic acid has greater combined (synergistic) absorption in the body, which may lead to future clinical trials and ultimately to a safe and effective treatment in patients diagnosed with prostate cancer to reduce the progression of disease.
    Location: Cancer Therapy and Research Center at The UT Health Science Center at San Antonio, San Antonio, Texas

  • Curcumin for the Treatment of Patients with Cervical Intraepithelial Neoplasia

    This randomized phase II trial studies curcumin to determine if it can clear human papillomavirus (HPV) infection or mild abnormal cells of the cervix in the treatment of patients with cervical intraepithelial neoplasia. These abnormal cells of the cervix are considered precancerous cells. Both invasive cervical cancers and precancerous cells have been firmly associated with the presence of high-risk HPV deoxyribonucleic acid (DNA). Not all precancerous cells progress to cancer. Curcumin, an extract from turmeric, a popular culinary spice, has been used in traditional Indian medicine for its anti-inflammatory and anti-infectious properties. Curcumin may slow down, destroy or prevent the growth of precancerous or cancer cells.
    Location: Grady Health System, Atlanta, Georgia

  • Curcumin in Reducing Joint Pain in Breast Cancer Survivors with Aromatase Inhibitor-Induced Joint Disease

    This phase I trial studies how well curcumin works in reducing joint pain in patients who are breast cancer survivors and have joint disease caused by treatment with aromatase inhibitors. Curcumin is an ingredient of turmeric, a plant in the ginger family, which is commonly used in curries and South Asian and Middle Eastern cooking, and may decrease joint pain in patients with arthritis from other conditions (such as osteoarthritis and rheumatoid arthritis).
    Location: 4 locations