Clinical Trials Using EphA2-targeting DOPC-encapsulated siRNA

Clinical trials are research studies that involve people. The clinical trials on this list are studying EphA2-targeting DOPC-encapsulated siRNA. All trials on the list are supported by NCI.

NCI’s basic information about clinical trials explains the types and phases of trials and how they are carried out. Clinical trials look at new ways to prevent, detect, or treat disease. You may want to think about taking part in a clinical trial. Talk to your doctor for help in deciding if one is right for you.

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  • EphA2 siRNA in Treating Patients with Advanced or Recurrent Solid Tumors

    This phase I trial studies the side effects and best dose of EphA2 siRNA in treating patients with solid tumors that have spread to other places in the body and usually cannot be cured or controlled with treatment (advanced) or have come back after a period of improvement (recurrent). EphA2-targeting DOPC-encapsulated siRNA may slow the growth of tumor cells by shutting down the activity of a gene that causes tumor growth.
    Location: M D Anderson Cancer Center, Houston, Texas