Clinical Trials Using Fluorine F 18 Fluorodopa
Clinical trials are research studies that involve people. The clinical trials on this list are studying Fluorine F 18 Fluorodopa. All trials on the list are supported by NCI.
NCI’s basic information about clinical trials explains the types and phases of trials and how they are carried out. Clinical trials look at new ways to prevent, detect, or treat disease. You may want to think about taking part in a clinical trial. Talk to your doctor for help in deciding if one is right for you.
18F-DOPA-PET / MRI Scan in Imaging Elderly Patients with Newly Diagnosed Grade IV Malignant Glioma or Glioblastoma during Planning for a Short Course of Proton Beam Radiation Therapy
This phase II trial studies how well fluorodopa F 18-positron emission tomography / magnetic resonance imaging scan (18F-DOPA-PET / MRI) works in imaging elderly patients with newly diagnosed grade IV malignant glioma or glioblastoma during planning for a short course of proton beam radiation therapy. 18F-DOPA is a chemical tracer that highlights certain cells during imaging. PET scan, is a metabolic imaging technique which takes advantage of how tumor cells take up nutrients differently than normal tissue. MRI scans are used to guide radiation therapy for most brain tumors. Hypofractionated proton beam therapy delivers higher doses of radiation therapy over a shorter period of time and may kill more tumor cells and have fewer side effects. Using 18FDOPA-PET scans along with MRI scans may be able to provide the radiation doctor with information on tumor tissue versus normal, healthy tissue and may help the doctor more accurately plan the radiation treatment.
Location: 2 locations
Fluorine F 18 Fluorodopa PET / MRI or PET / CT and Radiation Therapy in Treating Patients with Recurrent High-Grade Glioma
This pilot phase II trial studies how well fluorine F 18 fluorodopa positron emission tomography (PET) / magnetic resonance imaging (MRI) or PET / computed tomography (CT) and radiation therapy work in treating patients with high-grade glioma that has come back (recurrent). Fluorine F 18 fluorodopa PET / MRI or PET / CT may give doctors a better idea of where the disease is that needs to be treated with radiation, rather than using MRI alone. Radiation therapy uses high energy x-rays to kill tumor cells and shrink tumors.
Location: Mayo Clinic, Rochester, Minnesota
F-DOPA PET / CT in Finding Tumors in Patients With Suspected Recurrence of Glioblastoma
This randomized clinical trial studies fluorine F 18 fluorodopa (F-DOPA) positron emission tomography (PET) / computed tomography (CT) in finding tumors in patients with suspected recurrence of glioblastoma. New diagnostic procedures, such as fluorine F 18 fluorodopa PET / CT, may help find and diagnose glioblastoma recurrence.
Location: UCLA / Jonsson Comprehensive Cancer Center, Los Angeles, California