Clinical Trials Using Zirconium Zr 89 Trastuzumab

Clinical trials are research studies that involve people. The clinical trials on this list are studying Zirconium Zr 89 Trastuzumab. All trials on the list are supported by NCI.

NCI’s basic information about clinical trials explains the types and phases of trials and how they are carried out. Clinical trials look at new ways to prevent, detect, or treat disease. You may want to think about taking part in a clinical trial. Talk to your doctor for help in deciding if one is right for you.

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  • PET / MRI Imaging with 89Zr-Trastuzumab for Predicting Targeted Therapy Effectiveness in Patients with HER2 Positive Breast Cancer

    This phase I trial studies how well PET / MRI with imaging agent 89Zr-trastuzumab works for predicting target therapy effectiveness in patients with HER2 positive breast cancer. PET imaging is an established imaging technique that utilizes small amounts of radioactivity attached to very minimal amounts of tracer, in the case of this research, 89Zr-trastuzumab. MRI imaging uses radiofrequency waves and a strong magnetic field rather than x-rays to provide clear and detailed pictures of internal organs and tissues. 89Zr-trastuzumab works by binding to HER2 proteins on the cells, making it easier to take images of the tumor cells. Giving 89Zr-trastuzumab with PET / MRI may enhance imaging quality and may potentially spare patients from having to have multiple biopsies in the future.
    Location: University of Alabama at Birmingham Cancer Center, Birmingham, Alabama