Notice of Special Interest (NOSI): Research on HIV-associated Malignancies
The purpose of this Notice of Special Interest (NOSI) is to continue advancing our understanding of the risks, development, progression, diagnosis, and treatment of malignancies observed in individuals with an underlying human immunodeficiency virus (HIV) infection or acquired immunodeficiency syndrome (AIDS), which are now a leading cause of death of people with HIV (PWH). The NOSI calls for proposals that seek to identify specific contributions to HIV infection and it potential interaction with other oncogenic pathogens on the development and pathogenesis of these cancers, including studies that provide new information on the clinical outcomes of such cancers in PWH.
The purpose of this NOSI is therefore aligned with OAR priorities of AIDS research and is specifically launched to foster cancer-focused research that addresses important gaps in knowledge for the control and treatment of cancer and cancer-related comorbidities among PWH. This is a continuation of NOT-CA-20-022, "High" or "Medium" Priority AIDS Research on Non-AIDS-defining or AIDS-defining Cancers, which expired on January 8, 2023 , and is entitled, “Research on HIV-associated malignancies ” to reflect the most recent Office of AIDS Research priority guidelines.
Multidisciplinary Studies of HIV/AIDS and Aging
This initiative solicits applications at the intersection of HIV and aging. NCI is interested in studies that help to understand how aging in the presence of chronic HIV infections affects risk, spectrum and biology of cancer.
Additional Information:
Multidisciplinary Studies of HIV/AIDS and Aging (R01 Clinical Trial Optional)
Multidisciplinary Studies of HIV/AIDS and Aging (R21 Clinical Trial Optional)