NCI Funding for HIV and AIDS Malignancies Research
Investigations of the Transmission of Kaposi Sarcoma-Associated Herpesvirus (KSHV)
The purpose of these RFAs are to advance our understanding of the modes of transmission of Kaposi sarcoma-associated herpesvirus (KSHV), the biology of the initial steps of infection and risk factors that will inform efforts to prevent KSHV transmission and development of Kaposi sarcoma (KS) and other KSHV-associated diseases in people living with HIV and at risk of HIV infection.
HIV/AIDS and the Tumor Niche
The purpose of this RFA is to advance our understanding of the role of the tumor niche or microenvironment in the risks, development, progression, diagnosis, and treatment of cancer observed in individuals with an underlying HIV infection or Acquired Immune Deficiency Syndrome (AIDS).
HIV/AIDS and the Tumor Niche (R01)
Research on Non-AIDS-defining or AIDS-defining Cancers
The purpose of this initiative is to continue advancing our understanding of the risks, development, progression, diagnosis, and treatment of malignancies observed in individuals with an underlying human immunodeficiency (HIV) infection or acquired immunodeficiency syndrome (AIDS), particularly the non-AIDS defining malignancies which are now a leading cause of death in HIV-infected individuals. This FOA encourages research efforts that will (i) identify specific contributions resulting from HIV infection and its potential interaction with other pathogens for the development and pathogenesis of these cancers and (ii) provide information on the clinical outcomes of such cancers in the HIV-infected population. Ultimately, such efforts could inform screening approaches and therapies targeted to the HIV-infected population.
"High" or "Medium" Priority AIDS Research on Non-AIDS-defining or AIDS-defining Cancers (R01)
"High" or "Medium" Priority AIDS Research on Non-AIDS-defining or AIDS-defining Cancers (R21)
HIV and Hepatitis B Co-Infection: Advancing HBV Functional Cure Through Clinical Research
This initiative aims to fill scientific gaps needed to (a) inform HBV functional cure strategies by furthering our understanding of unique challenges impacting HBV and HIV co-infected hosts and (b) advance the discovery and development of novel HBV interventions that are safe and achieve a functional cure in HIV and HBV co-infected individuals.
HIV and Hepatitis B Co-Infection: Advancing HBV Functional Cure through Clinical Research (R01)
HIV and Hepatitis B Co-Infection: Advancing HBV Functional Cure through Clinical Research (R21)
In Vitro and Animal Model Studies on HBV/HIV Co-Infection
This initiative solicits application that will (a) stimulate and accelerate development of novel in vitro and small animal models of HBV/HIV co-infection to accelerate drug discovery/drug development in HBV/HIV co-infection; and (b) stimulate and accelerate a better understanding of the immunopathogenic interactions between HBV and HIV.
Multidisciplinary Studies of HIV/AIDS and Aging
This initiative solicits applications at the intersection of HIV and aging. NCI is interested in studies that help to understand how aging in the presence of chronic HIV infections affects risk, spectrum and biology of cancer.Additional Information:
Harnessing Big Data to Halt HIV
This funding opportunity announcement (FOA) encourages applications that will transform understanding of HIV transmission, the HIV care continuum, and HIV comorbidities using Big Data Science (BDS). NIH is interested in promoting and applying Big Data Science technologies, computing, informatics, and analytics to address gaps in our understanding of HIV transmission risks, social networks, and the HIV treatment continuum including comorbidities such as cancer.Additional Information:
Tobacco Use and HIV in Low and Middle Income Countries
This initiative encourages research focused on tobacco use and HIV in low and middle income countries. In particular, applications focused on the development and evaluation of tobacco cessation interventions targeted to HIV positive persons are encourated.Additional Information:
Reducing Stigma to Improve HIV/AIDS Prevention, Treatment and Care in Low and Middle Income Countries
NCI is interested in encouraging applications that propose evidence based studies to reduce cancer stigma among healthcare providers, caregivers and cancer patients living with HIV/AIDS.