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NCI Organization

As the nation's leading federal agency for cancer research, NCI has 30 divisions, offices, and centers who work together to build, maintain, and enhance a cohesive and comprehensive cancer research agenda. Their work ranges from cutting-edge research on cancer causes, treatment, and prevention; to training the next generation of cancer researchers; to funding and supporting the nation's vast network of scientists and cancer research institutions; to informing and educating the American public and the world about cancer. The NIH Office of Management Assessment maintains the official NCI organization chart.

NCI Divisions and Centers



CCR houses a productive community of NCI intramural basic researchers, clinicians, and translational scientists who integrate basic and clinical research discovery to develop novel therapeutic interventions which better treat adults and children with cancer or HIV.


DCEG is the world’s most comprehensive cancer epidemiology research group. Its renowned epidemiologists, geneticists, and biostatisticians conduct population and multidisciplinary research to discover the genetic and environmental determinants of cancer and new approaches to cancer prevention.




DCB encourages and facilitates continued support of basic research in all areas of cancer biology to provide the research foundation which enables improved understanding of the disease and may lead to new approaches for prevention, diagnosis, and treatment.


DCCPS conducts and supports an integrated program of genetic, epidemiological, behavioral, social, applied, and surveillance cancer research to reduce risk, incidence, and deaths from cancer as well as enhance the quality of life for cancer survivors.


DCP conducts and supports research to find ways to prevent and detect cancer, and to prevent or relieve symptoms from cancer and its treatments.


DCTD supports the translation of promising research into clinical applications to improve the diagnosis and treatment of cancer in areas of unmet need that are often too risky or difficult for industry or academia to develop alone.


DEA coordinates the scientific review of extramural research before funding and provides systematic surveillance of that research after awards are made to assist the NCI in achieving its goal of a balanced research portfolio.


NCI Office of the Director

  • Center for Biomedical Informatics and Information Technology (CBIIT)

    Collaborates across NCI to plan, provide, and coordinate technology, standards, and scientific computing in support of the NCI mission to speed discovery, facilitate open science, and progress towards precision treatment in cancer care and a learning healthcare system.

  • Center for Cancer Genomics

    Unifies NCI's activities in cancer genomics by aiming to synthesize research in different fields of cancer genomics – structural, functional, and computational – to improve patient outcomes.

  • Center for Cancer Training (CCT)

    Provides funding to support training and career development at institutions nationwide and manages training programs at NCI’s laboratories, clinics, and research groups to develop a 21st century workforce capable of advancing cancer research.

  • Center for Global Health (CGH)

    Provides assistance and guidance to nations as they develop and implement cancer control plans, trains international investigators, and strengthens U.S. national, regional, multilateral, and bilateral collaboration in health research, cancer research, and cancer control to advance global cancer research, build expertise, and reduce cancer deaths worldwide.

  • Center for Cancer Health Equity (CCHE)

    Conducts basic, clinical, translational, and population-based cancer disparities research; trains the next generation of competitive cancer researchers from diverse populations; and creates regional cancer health disparities networks to reduce the unequal burden of cancer in our society.

  • Center for Research Strategy (CRS)

    Conducts analysis, evaluation, and planning activities to support strategic decision making for program management, policy making, and strategic planning while identifying cross-cutting opportunities and collaborating on various initiatives to advance the mission of NCI.

  • Center for Strategic Scientific Initiatives (CSSI)

    Creates and implements exploratory programs focused on emerging scientific discoveries and innovative technologies to accelerate the pace of cancer research and the translation of research results into new therapies, diagnostics, and preventive agents.

  • Coordinating Center for Clinical Trials (CCCT)

    Facilitates efforts across NCI to enhance the effectiveness of the NCI's clinical trials enterprise through collaboration and harmonization among NCI programs and extramural stakeholder communities.

  • Ethics Office

    Manages all aspects of a comprehensive ethics program to ensure employees and others working with NCI comply with ethics policies.

  • Office of Workforce Strategy and Effectiveness

    Advises NCI leadership on organizational performance and efficiency and provides coordinated policies, programs, services, tools, and resources to optimize organizational health, individual performance, and employee engagement.

  • Office of Acquisitions (OA)

    Plans, negotiates, awards, and administers NCI contracts and simplified acquisitions to support a coordinated cancer research program.

  • Office of Advocacy Relations (OAR)

    Serves as the cancer advocacy community's primary point of contact and facilitates the involvement of advocates in NCI's research activities to help enhance the scientific process and improve patient outcomes.

  • Office of Budget and Finance (OBF)

    Advises the Office of the Director and other senior staff on the management of financial and personnel resources to ensure fiscally responsible and efficient operation of the Institute.

  • Office of Cancer Centers (OCC)

    Supports 72 NCI-designated cancer centers nationwide that are actively engaged in trans-disciplinary research to reduce cancer incidence, morbidity, and mortality.

  • Office of Communications and Public Liaison (OCPL)

    Supports NCI by disseminating cancer research findings, providing evidence-based information on cancer for the public, including patients, caregivers, health professionals, researchers, advocates, the news media, and other stakeholders, and disseminating information about cancer clinical trials and funding opportunities.

  • Office of Grants Administration (OGA)

    Manages all NCI business-related activities associated with the negotiation, award, and administration of NCI grants and cooperative agreements to help financially support cancer research activities throughout the United States and around the world.

  • Office of Government and Congressional Relations (OGCR)

    Informs the NCI community of congressional issues and interests that affect the Institute; facilitates relationships between NCI, Congress, and the public; and responds to Freedom of Information Act and Government Accountability Office requests to foster an understanding of the scope and value of NCI's investment in cancer research.

  • Office of HIV and AIDS Malignancy (OHAM)

    Coordinates and oversees HIV/AIDS and HIV/AIDS cancer research; directly manages certain HIV/AIDS-cancer research activities; and acts as a point of contact for the NIH Office of AIDS Research and other Institutes and Centers to enhance HIV/AIDS and HIV malignancies research efforts across NCI.

  • Office of Management (OM)

    Oversees NCI’s business and administrative activities, advises the NCI Director and senior staff on management issues, and leads a variety of programs vital to NCI’s administrative operations.

  • Office of Scientific Operations, NCI Frederick (OSO)

    The NCI Frederick campus, which includes the Frederick National Laboratory for Cancer Research, is located about 40 miles northwest of the NIH main campus in Bethesda, Maryland. The Frederick National Lab is a federally funded research and development center that conducts biomedical research on cancer and infectious disease.

  • SBIR Development Center (SBIR & STTR)

    Seeks to increase small business and private sector participation to develop and commercialize novel technologies and products to help advance cancer research, prevention, diagnosis and treatment.

  • Technology Transfer Center (TTC)

    Builds partnerships and fosters collaboration agreements between NIH scientists, universities, non-profits, and industry to commercialize NIH inventions, and supports research and development that benefits public health.