Office of HIV and AIDS Malignancy
The NCI has played a major role in HIV/AIDS research since the beginning of the epidemic, when a cluster of cases of Kaposi's sarcoma was one of the harbingers of this new disease. NCI scientists have made a number of key discoveries in both HIV/AIDS and AIDS-associated cancer. Today, this research is coordinated by the Office of HIV and AIDS Malignancy (OHAM) and carried out in multiple divisions and offices of the NCI.
Research Activities
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AIDS and Cancer Specimen Resource
Learn how ACSR encourages pivotal study of the HIV/AIDS epidemic and its impact on cancer incidence.
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AIDS Malignancy Consortium
Learn more about AMC’s commitment to supporting innovation in clinical trials.
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International Conference on Malignancies in HIV/AIDS (ICMH)
Save the date for the 20th International Conference on Malignancies in HIV/AIDS (ICMH): April 15-16, 2027 at the Lister Hill Center Auditorium, NIH.
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Strengthening Capacity for Research for HIV-Associated Malignancies in LMICs
Find a list of research centers and initiatives dedicated to HIV-associated cancers in Low- and Middle- Income Countries (LMIC).
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Learn more about OHAM Research Activities
OHAM manages four research programs and shares oversight for HIV/AIDS research activities across NCI and NIH.
Research News
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Cancer Immunotherapy Trials Network 12: Pembrolizumab in HIV-Associated Kaposi Sarcoma
NCI researchers and the Immunotherapy Trials Network 12 demonstrated the safety of pembrolizumab HIV-associated Kaposi sarcoma (KS). Pembrolizumab use also resulted in a high rate of durable responses HIV-associated KS.
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Antibody profiling and predictive modeling discriminate between Kaposi sarcoma and asymptomatic KSHV
OHAM supported investigators recently published a study that provides the highest resolution mapping of antigenicity across the entire KSHV proteome.
Patient Information about HIV-Associated Malignancies
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Infectious Agents
Certain infectious agents, including viruses, bacteria, and parasites, can cause cancer in infected people or increase the risk that cancer will form.
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HIV Infection and Cancer
Persons with HIV are at increased risk of certain types of cancer. Learn more from this fact sheet, including ways to lower the risk or find cancer early.