Learn about upcoming meetings relevant to HIV malignancies and recent news about NCI HIV/AIDS and HIV malignancy research.
Investigators at NCI identify the receptor for one of the HLA proteins (HLA-E) as a potential new target for HIV treatment. Blockade of this pathway has been implicated in many cancers and autoimmune diseases.
People living with HIV have an increased cancer burden, even in the absence of over immunosuprresion. In this review, NCI researchers Drs. Yarchoan and Uldrick describe the current epidemiology, pathogenesis and prevention strategies of HIV-associated cancers and related diseases.
NCI supported researchers have determined the structure of the Kaposi sarcoma-associated herpesvirus (KSHV), also called human herpesvirus 8. This may provide a target for the developement of antiviral agents.