NCI Drug Dictionary

The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

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CAR-T cells AMG 119
A preparation of T lymphocytes that are genetically engineered to express a chimeric antigen receptor (CAR) that targets an as of yet unidentified tumor-associated antigen (TAA), with potential immunomodulatory and antineoplastic activities. Upon administration of the CAR T-cells AMG 119, the T cells target, bind to and induce selective cytotoxicity in tumor cells expressing the TAA. Check for active clinical trials using this agent. (NCI Thesaurus)

Synonym:AMG 119 CAR-T cells
Code name:AMG 119
AMG119
AMG-119