NCI Drug Dictionary

The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

CAR-T cells AMG 119
A preparation of T lymphocytes that are genetically engineered to express a chimeric antigen receptor (CAR) that targets an as of yet unidentified tumor-associated antigen (TAA), with potential immunomodulatory and antineoplastic activities. Upon administration of the CAR T-cells AMG 119, the T cells target, bind to and induce selective cytotoxicity in tumor cells expressing the TAA. Check for active clinical trials using this agent. (NCI Thesaurus)

Synonym:AMG 119 CAR-T cells
Code name:AMG 119