NCI Drug Dictionary

The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

Browse:
carbon C 11-osimertinib
A radioconjugate composed of osimertinib, a third-generation, orally available, irreversible, mutant-selective, epidermal growth factor receptor (EGFR) inhibitor, labeled with the positron-emitting isotope carbon C 11, with potential use in imaging via positron emission tomography (PET). Upon intravenous administration of carbon C 11 osimertinib, the osimertinib targets and binds to mutant forms of EGFR on tumor cells. Upon PET imaging, this radioligand may allow for the assessment of EGFR mutant-expressing tumor cells. This also allows assessment of osimetinib’s pharmacokinetic profile and affinity of EGFR mutant-positive cancer cells and may identify patients who may respond well to osimertinib. Check for active clinical trials using this agent. (NCI Thesaurus)

Synonym:[11C] osimertinib
[11C]AZD9291
11C-osimertinib