acodazole
A synthetic imidazoquinoline with antineoplastic activity. Acodazole intercalates into DNA, resulting in disruption of DNA replication. Use of this agent has been associated with significant cardiotoxicity.
| Synonym: | acodazole hydrochloride |
|---|---|
| Chemical structure: | 1H-imidazo[4,5-f]quinoline, acetamide deriv acetamide, N-methyl-N-[4-[(7-methyl-1H-imidazo[4, 5-f]quinolin-9-yl)amino]phenyl]- acetamide, N-methyl-N-[4-[(7-methyl-1H-imidazo[4, 5-f]quinolin-9-yl)amino]phenyl]-, monohydrochloride (9CI) |
| IND number: | 21351 |
| NSC code: | 305884 |