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allogeneic nicotinamide-expanded natural killer cells

Allogeneic, nicotinamide (NAM)-expanded natural killer (NK) cells, with potential cytolytic and antineoplastic activities. Upon administration, the allogeneic NAM-expanded NK cells may lyse cancer cells. These cells also secrete pro-inflammatory cytokines, which further stimulate an anti-tumor immune response. Ex-vivo treatment with the vitamin B3 derivative NAM increases the in-vivo homing, retention and proliferation potential of the NK cells.
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Synonym:allogeneic NAM NK cells
allogeneic NAM NKs
donor nicotinamide-expanded natural killer cells
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