NCI Drug Dictionary

The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

aminolevulinic acid
A topically administered metabolic precursor of protoporphyrin IX. After topical administration, aminolevulinic acid (ALA) is converted to protoporphyrin IX (PpIX) which is a photosensitizer. When the proper wavelength of light activates protoporphyrin IX, singlet oxygen is produced, resulting in a local cytotoxic effect. Check for active clinical trials using this agent. (NCI Thesaurus)

Synonym:5-aminolaevulinic acid
5-aminolevulinic acid
amino-levulinic acid
delta aminolevulinic acid
delta-aminolevulinic acid
Chemical structure:
  • 5-amino-4-oxopentanoic acid
  • d-amino-levulinic acid