NCI Drug Dictionary

The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

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aminothiadiazole
A synthetic derivative of nicotinamide adenine dinucleotide (NAD). Aminothiadiazole competitively inhibits inosine 5-monophosphate dehydrogenase, thereby disrupting the regulation of cell proliferation and differentiation in a number of cells. This agent is also a selective human adenosine A3 receptor antagonist. Check for active clinical trials using this agent. (NCI Thesaurus)

Synonym:2-Aminothiadiazole
Amino 134-Thiadiazole
Abbreviation:A-TD
ATDA
Code name:FDA 0084
Chemical structure:
  • 1,3, 4-Thiadiazol-2-amine (9CI)
  • 1,3, 4-Thiadiazole, 2-Amino- (8CI)
  • 1,3,4-Thiadiazole, 2-Amino
  • 2-Amino-1,3,4-thiadiazole
  • 2-Amino-1-thia-3,4-diazole