NCI Drug Dictionary
The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.
A synthetic derivative of nicotinamide adenine dinucleotide (NAD). Aminothiadiazole competitively inhibits inosine 5-monophosphate dehydrogenase, thereby disrupting the regulation of cell proliferation and differentiation in a number of cells. This agent is also a selective human adenosine A3 receptor antagonist. Check for active clinical trials using this agent. (NCI Thesaurus)
Code name: FDA 0084 Chemical structure:
- 1,3, 4-Thiadiazol-2-amine (9CI)
- 1,3, 4-Thiadiazole, 2-Amino- (8CI)
- 1,3,4-Thiadiazole, 2-Amino