NCI Drug Dictionary

The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

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anguidine
A trichothecene mycotoxin and potent teratogen. Anguidine inhibits initiation of protein synthesis, resulting in the death of rapidly proliferating cells. Anguidine also has been shown to both potentiate and protect against the cytotoxic effects of other drugs. Check for active clinical trials using this agent. (NCI Thesaurus)

Synonym:Anguidin
diacetoxyscirpenol
Abbreviation:DAS
Code name:MM 4462
Chemical structure:
  • 3.alpha,4.beta, 15-triol, 12, 13-epoxy-,4, 15-diacetate (8CI)
  • 4, 15-diacetoxyscirpen-3-ol
  • 4.beta, 15-diacetoxy-3.alpha-hydroxy-12, 13-epoxytrichothec-9-ene
  • trichothec-9-ene-3, 4, 15-triol, 12, 13-epoxy-, 4, 15-diacetate (3.alpha, 4.beta)-(9CI)
  • trichothec-9-ene-3,4, 15-triol, 12,13-epoxy-, 4,15-diacetate