anti-AG7 antibody drug conjugate AbGn-107
An antibody drug conjugate (ADC) composed of a monoclonal antibody that targets the tumor-associated antigen (TAA) AG7 and is linked, through a hydrophilic, self-immolative linker, to a proprietary cytotoxic payload, with potential antineoplastic activity. Upon administration of AbGn-107 the antibody moiety targets and binds to the AG7 antigen expressed on a variety of cancer cells. Upon binding and internalization, the linker is cleaved and the payload is released, binds to tubulin, inhibits tubulin polymerization and kills the AG7-expressing tumor cells.
Synonym: | Ab1-18Hr1 AbGn107 ADC AbGn-107 anti-AG7 ADC AbGn-107 |
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Code name: | AbGn-107 |