NCI Drug Dictionary

The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

anti-EGFR fluorescence imaging agent ABY-029
A fluorescence imaging and contrast agent composed of an epidermal growth factor receptor (EGFR)-targeting affibody tracer molecule and labeled, through maleimide, with a near-infrared (NIR) fluorescent probe, IRDye 800CW, with potential use in the imaging of EGFR-overexpressing cells. Upon administration, ABY-029 targets and binds to EGFR-overexpressing tumor cells. Upon fluorescent imaging, the fluorescent dye can be visualized and EGFR-positive tumor cells can be detected. Check for active clinical trials using this agent. (NCI Thesaurus)

Synonym:ABY-029 trifluoroacetate salt
fluorescently-labeled Anti-EGFR affibody molecule ABY-029
IRDye 800CW maleimide-labeled affibody peptide
Code name:ABY-029