NCI Drug Dictionary

The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

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anti-EGFR fluorescence imaging agent ABY-029
A fluorescence imaging and contrast agent composed of an epidermal growth factor receptor (EGFR)-targeting affibody tracer molecule and labeled, through maleimide, with a near-infrared (NIR) fluorescent probe, IRDye 800CW, with potential use in the imaging of EGFR-overexpressing cells. Upon administration, ABY-029 targets and binds to EGFR-overexpressing tumor cells. Upon fluorescent imaging, the fluorescent dye can be visualized and EGFR-positive tumor cells can be detected. Check for active clinical trials using this agent. (NCI Thesaurus)

Synonym:ABY-029 trifluoroacetate salt
fluorescently-labeled Anti-EGFR affibody molecule ABY-029
IRDye 800CW maleimide-labeled affibody peptide
Code name:ABY-029