NCI Drug Dictionary

The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

A synthetic chlorophenyl-butanoic acid derivative with muscle relaxant activity. Baclofen acts as a gamma-aminobutyric acid (GABA) agonist specific for GABA-B receptors in the central nervous system (CNS). At spinal and supraspinal sites, this agent reduces excitatory transmission. Check for active clinical trials using this agent. (NCI Thesaurus)

US brand name:Lioresal
Code name:BA34647
Chemical structure:
  • 4-Amino-3-(4-chlorophenyl)-butanoic Acid
  • beta-(Aminomethyl)-4-chlorobenzenepropanoic acid