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bavituximab

A chimeric, IgG1 monoclonal antibody directed against anionic phospholipids with potential antineoplastic activity. Bavituximab binds to anionic phospholipids in a beta 2-glycoprotein I-dependent manner, inhibiting tumor growth by stimulating antibody-dependent cellular cytotoxicity (ADCC) to tumor vessels.
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Synonym:chimeric anti-phosphotidylserine monoclonal antibody
US brand name:Tarvacin
Code name:PGN401
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