NCI Drug Dictionary

The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

A 17-alkylated orally active androgenic steroid. Calusterone may alter the metabolism of estradiol and reduce estrogen production. Check for active clinical trials using this agent. (NCI Thesaurus)

US brand name:Methosarb
Code name:U-22,550
Chemical structure:
  • 17 beta-OH-7 beta, 17 alpha-dimethyl-androst-4-ene-3-one
  • 17-beta-hydroxy-7-beta, 17-dimethylandrost-4-ene-3-one
  • 7 beta, 17 alpha-dimethyltestosterone
  • androst-4-en-3-one, 17.beta.-hydroxy-7.beta.,17-dimethyl- (8CI)
  • androst-4-en-3-one, 17-hydroxy-7,17-dimethyl-, (7.beta.17.beta.)- (9CI)
  • androst-4-en-3-one, 7.beta., 17.alpha.-dimethyl-17.beta.-hydroxy-