carcinoembryonic antigen peptide 1
A nine amino acid peptide fragment of carcinoembryonic antigen (CEA), a protein that is overexpressed in several cancer cell types, including gastrointestinal, breast, and non-small cell lung. Autologous vaccination with activated autologous dendritic cells (DC) or peripheral blood mononuclear cells (PBMC) which have been exposed to CEA peptide 1 in vitro may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells expressing CEA, thereby inhibiting tumor growth.
| Synonym: | CAP-1 Carcinoembryonic Antigen Peptide-1 Carcinoembryonic Peptide-1 CEA Peptide 1 CEA Peptide 9-mer |
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| IND number: | 6843 |
| NSC code: | 672683 |