NCI Drug Dictionary

The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

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clindamycin/hydrocortisone lotion
A topical lotion, containing clindamycin and hydrocortisone, with antibacterial and anti-inflammatory activities. Clindamycin, a lincomycin antibiotic, binds to the 50S subunit of the bacterial ribosome, thereby inhibiting bacterial protein synthesis. As a glucocorticoid agonist, hydrocortisone promotes protein catabolism, gluconeogenesis, capillary wall stability, renal excretion of calcium, and suppression of immune and inflammatory responses. Check for active clinical trials using this agent. (NCI Thesaurus)