cold contaminant-free Iobenguane I-131
An I 131 radioiodinated synthetic analogue of the neurotransmitter norepinephrine, manufactured with a proprietary process, with radioisotopic and potential antineoplastic activities. Cold contaminant-free iobenguane I 131 (MIBG) localizes to adrenergic tissue and may be used to image or eradicate tumor cells that accumulate and metabolize norepinephrine. This agent is manufactured using a technology that avoids the production of unwanted "cold contaminants" (i.e., carrier molecules), which may cause undesirable side effects and compete with MIBG for binding on target receptor sites.
Synonym: | cold contaminant-free I 131-MIBG cold contaminant-free iobenguane I 131 cold contaminant-free iodine I 131 metaiodobenzylguanidine ultratrace iodine I 131 metaiodobenzylguanidine |
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US brand name: | Azedra |
Abbreviation: | Ultratrace MIBG |