Skip to main content
An official website of the United States government

defibrotide sodium

View Patient Information
A polydeoxyribonucleotide with antithrombotic, thrombolytic, and fibrinolytic properties. Defibrotide sodium induces the release of prostaglandin 12 and reduces the expression of adhesion molecules on endothelial cells, thereby interfering with platelet and leukocyte adhesion to the endothelium.
Check for active clinical trials using this agentView this agent in the NCI Thesaurus
US brand name:Defitelio
Search NCI's Drug Dictionary
Please enter up to 30 characters for your search