NCI Drug Dictionary

The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

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dextroamphetamine sulfate
The salt of the dextro-isomer of amphetamine and sympathomimetic amine with CNS stimulating properties. Dextroamphetamine sulphate acts by facilitating the release of catecholamines, particularly noradrenaline and dopamine, from nerve terminals in the brain and inhibits their uptake. This leads to an increase in motor activity, causes euphoria, mental alertness and excitement and suppresses appetite. This drug causes dependence and may cause an increase in heart rate and blood pressure. It is used in the treatment of narcolepsy and attention deficit hyperactivity disorder. Check for active clinical trials using this agent. (NCI Thesaurus)

Synonym:d-amphetamine sulphate
US brand name:Dexampex
Dexedrine
Dextrostat
Ferndex
Chemical structure:
  • (+)-alpha-methylphenethylamine sulphate (2:1)
  • (S)-alpha-methylbenzeneethanamine sulfate
  • benzeneethanamine, alpha-methyl-, (S)-, sulfate (2:1)
  • d-alpha-methylphenethylamine sulfate