recombinant interleukin-12
A recombinant form of the endogenous heterodimeric cytokine interleukin-12 with potential antineoplastic activity. Recombinant interleukin-12 binds to and activates its cell-surface receptor, stimulating the production of interferon-gamma (IFN) which, in turn, induces IFN-gamma-inducible protein-10 (IP-10) and so inhibits tumor angiogenesis.
| Synonym: | cytotoxic lymphocyte maturation factor interleukin-12 natural killer cell stimulatory factor NM-IL-12 recombinant human interleukin-12 (IL-12) cytokine |
|---|---|
| Abbreviation: | IL-12 |
| Code name: | Ro 24-7472 |
| IND number: | 6123 6419 6798 7103 8748 |
| NSC code: | 672423 |