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recombinant interleukin-12

A recombinant form of the endogenous heterodimeric cytokine interleukin-12 with potential antineoplastic activity. Recombinant interleukin-12 binds to and activates its cell-surface receptor, stimulating the production of interferon-gamma (IFN) which, in turn, induces IFN-gamma-inducible protein-10 (IP-10) and so inhibits tumor angiogenesis.
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Synonym:cytotoxic lymphocyte maturation factor
interleukin-12
natural killer cell stimulatory factor
NM-IL-12
recombinant human interleukin-12 (IL-12) cytokine
Abbreviation:IL-12
Code name:Ro 24-7472
IND number:6123
6419
6798
7103
8748
NSC code:672423
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