efaproxiral
A synthetic small molecule with radiosensitizing activity. Efaproxiral increases oxygen levels in hypoxic tumor tissues by binding non-covalently to the hemoglobin tetramer and decreasing hemoglobin-oxygen binding affinity. Increasing tumor oxygenation reduces tumor radioresistance.
Synonym: | 2-dacmpp Efaproxyn |
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Code name: | RSR13 |
Chemical structure: | 2-(4-(((3,5-dimethylanilino)Carbonyl)methyl)phenoxy)-2-methylpropionic acid |
NSC code: | 950116 |