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fluorine F 18-6-fluorodopamine

A radioconjugate consisting of 6-fluorodopamine labeled with fluorine F18 (6-[18F]FDA), with potential diagnostic activity. Upon administration, 6-[18F]FDA is taken up by presynaptic sympathetic nerve endings via the norepinephrine transporter (NET) uptake-1. Once inside, 6-[18F]FDA is rapidly converted by dopamine-beta-hydroxylase into 6-[18F]fluoronorepinephrine (6-[18F]FNE) and stored into neuronal storage vesicles. Upon positron emission tomographic (PET) scanning of the F18, sympathetic innervated regions can be visualized, such as those in pheochromocytoma.
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Synonym:18F-fluorodopamine
18F]-6F-dopamine
3,4-dihydroxy-6-fluorophenethylamine F-18
6-fluorodopamine F-18
fluorine F 18 6-fluorodopamine
Abbreviation:[18F]-6F-DA
18F-DA
6-[18F]FDA
Chemical structure:1,2-benzenediol, 4-(2-aminoethyl)-5-(fluoro-18F)-
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