NCI Drug Dictionary

The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

fluorine F 18 fluorodopa
The amino acid analog fluorodopa (FDOPA) labeled with fluorine F 18, a positron-emitting isotope, with potential tumor tracer property. Fluorine F 18 fluorodopa is able to cross the blood-brain barrier and is taken up by brain tumor cells. As uptake is higher in tumor cells, tumors may then be imaged using positron emission tomography (PET). Assessing tumor uptake of FDOPA may be beneficial for diagnosis, localization and in determining further treatment. Check for active clinical trials using this agent. (NCI Thesaurus)

18F-6- L-fluorodopa
Chemical structure:
  • 3,4-dihydroxy-6-(18)F-fluoro-l-phenylalanine
  • L-6-[ 18F]fluoro-3, 4-dihydroxyphenylalanine