NCI Drug Dictionary

The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

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eftilagimod alpha
A T-cell immunostimulatory factor, derived from the soluble form of the lymphocyte-activation gene 3 (LAG-3) protein, with potential antineoplastic activity. Upon administration, alone or in combination with tumor antigens, eftilagimod alpha binds with high affinity to MHC class II molecules expressed by dendritic cells (DC), potentially resulting in DC maturation, DC migration to lymph nodes, enhanced DC cross-presentation of antigens to T cells, and antitumor cytotoxic T cell responses. Check for active clinical trials using this agent. (NCI Thesaurus)

Synonym:Efti
hLAG-31g
LAG-3Ig
LAG-3-Ig-fusion protein
sLAG-3-Ig
Foreign brand name:ImmuFact IMP321
ImmuFact-IMP321
Code name:EDP-202
EOC-202
IMP321
IMP-321