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itraconazole

A synthetic triazole agent with antimycotic properties. Formulated for both topical and systemic use, itraconazole preferentially inhibits fungal cytochrome P450 enzymes, resulting in a decrease in fungal ergosterol synthesis. Because of its low toxicity profile, this agent can be used for long-term maintenance treatment of chronic fungal infections.

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Synonym:	oriconazole
US brand name:	Lozanoc Sporanox
Foreign brand name:	Lozanoc
Code name:	R 51,211
Chemical structure:	(+-)-1-sec-butyl-4-(p-(4-(p-(((2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)-1-piperazinyl)phenyl)-delta(sup 2)-1,2,4-triazolin-5-one

itraconazole

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