Skip to main content
An official website of the United States government

ONYX-015

An E1B-55kDa-deleted adenovirus that is able to selectively replicate in and lyse TP53-deficient human tumor cells. After tumor cell lysis, released viruses infect neighboring tumor cells, tripping a chain of ONYX-015-mediated tumor cell cytotoxicity.
Check for active clinical trials using this agentView this agent in the NCI Thesaurus
Synonym:E1B 55kDa mutant adenovirus dl1520
Code name:CI-1042
IND number:7872
NSC code:688653
Search NCI's Drug Dictionary
Please enter up to 30 characters for your search