NCI Drug Dictionary

The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

methylmercaptopurine riboside
A purine derivative with antineoplastic and anti-angiogenic properties. 6-methylmercaptopurine riboside (6-MMPR) inhibits amidophosphoribosyltransferase, the first committed step in de novo purine synthesis, and inhibits fibroblast growth factor-2 (FGF2)-induced cell proliferation. Check for active clinical trials using this agent. (NCI Thesaurus)

Code name:NCI-C04784
SQ 21977
Chemical structure:
  • 6-(methylmercapto)purine ribonucleoside
  • 6-(methylthio) inosine
  • 6-(methylthio)purine ribonucleoside
  • 6-(methylthio)purine riboside
  • 6-methyl MP riboside
  • 6-methylmercaptopurine riboside
  • 6-methylthioinosine
  • 9H-purine, 6-(methylthio)-9beta-D-ribofuranosyl
  • 9H-purine, 6-(methylthio)-9-beta-D-ribofuranosyl- (8CI 9CI)
  • 9H-purine, 6-(methylthio)-9-beta-D-ribofuranosyl-, dihydrate
  • beta-D-ribosyl-6-methylthiopurine
  • purine-6-thiol,6-methyl-9-ribofuranosyl