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nesvacumab

A fully human monoclonal antibody directed against angiopoietin 2 (ANG2) with potential antiangiogenic and antineoplastic activities. Nesvacumab binds to ANG2 and interferes with the interaction between Ang2 and its receptor TEK tyrosine kinas e (Tie2), which may inhibit tumor cell angiogenesis and tumor cell proliferation. ANG2 is upregulated in a variety of cancer cell types and plays a crucial role in angiogenesis.

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Synonym:	anti-ANG2 MoAb REGN910 anti-ANG2 monoclonal antibody REGN910
Code name:	REGN910 SAR307746

nesvacumab

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