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nimustine

A nitrosourea with antineoplastic activity. Nimustine alkylates and crosslinks DNA, thereby causing DNA fragmentation, inhibition of protein synthesis, and cell death.
Synonym:Nimustine Hydrochloride
pimustine hydrochloride
US brand name:ACNU 50
Foreign brand name:Nidran
Abbreviation:ACNU
Chemical structure:N'-[4-amino-2-methyl-5-pyrimidinyl)methyl]-N-(2-chloroethyl)-N-nitrosourea
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