nimustine
A nitrosourea with antineoplastic activity. Nimustine alkylates and crosslinks DNA, thereby causing DNA fragmentation, inhibition of protein synthesis, and cell death.
| Synonym: | Nimustine Hydrochloride pimustine hydrochloride |
|---|---|
| US brand name: | ACNU 50 |
| Foreign brand name: | Nidran |
| Abbreviation: | ACNU |
| Chemical structure: | N'-[4-amino-2-methyl-5-pyrimidinyl)methyl]-N-(2-chloroethyl)-N-nitrosourea |