nimustine
A nitrosourea with antineoplastic activity. Nimustine alkylates and crosslinks DNA, thereby causing DNA fragmentation, inhibition of protein synthesis, and cell death.
Synonym: | Nimustine Hydrochloride pimustine hydrochloride |
---|---|
US brand name: | ACNU 50 |
Foreign brand name: | Nidran |
Abbreviation: | ACNU |
Chemical structure: | N'-[4-amino-2-methyl-5-pyrimidinyl)methyl]-N-(2-chloroethyl)-N-nitrosourea |