pegdinetanib
A highly specific, synthetic peptide vascular endothelial growth factor receptor-2 (VEGFR-2) antagonist with potential antiangiogenic activity. Derived from human fibronectin with a proprietary protein engineering process, pegdinetanib may block the activation of VEGFR-2 by all known activating ligands, thereby inhibiting the growth of new tumor blood vessels.
Synonym: | VEGFR-2 inhibitor peptide CT-322 |
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US brand name: | Angiocept |
Code name: | CT-322 |