NCI Drug Dictionary

The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

perillyl alcohol
A naturally occurring monoterpene related to limonene with antineoplastic activity. Perillyl alcohol inhibits farnesyl transferase and geranylgeranyl transferase, thereby preventing post-translational protein farnesylation and isoprenylation and activation of oncoproteins such as p21-ras, and arresting tumor cells in the G1 phase of the cell cycle. Check for active clinical trials using this agent. (NCI Thesaurus)

Synonym:dihydrocuminyl alcohol
perilla alcohol
perillic alcohol
Code name:NEO100
Chemical structure:
  • (S)-(-)-perillyl alcohol
  • 1-cyclohexene-1-methanol
  • 4-(1-methylethenyl)-1-cyclohexene-1-methanol
  • 4-isopropenylcyclohex-1-ene-1-methanol
  • p-mentha-1,8-dien-7-ol