NCI Drug Dictionary

The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

A new generation organic platinum analog with an extended spectrum of antineoplastic activity. Designed to overcome platinum drug resistance, picoplatin alkylates DNA, forming both inter- and intra-strand cross-linkages, resulting in inhibition of DNA replication and transcription, and the induction of apoptosis. Check for active clinical trials using this agent. (NCI Thesaurus)

Code name:AMD473
NX 473
Chemical structure:
  • Cis-Amminedichloro (2-Methylpyridine) Platinum
  • Platinum, Amminedichloro(2-methylpyridine)-, (SP-4-3)