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picoplatin

A new generation organic platinum analog with an extended spectrum of antineoplastic activity. Designed to overcome platinum drug resistance, picoplatin alkylates DNA, forming both inter- and intra-strand cross-linkages, resulting in inhibition of DNA replication and transcription, and the induction of apoptosis.

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Code name:	AMD473 NX 473 ZD0473
Chemical structure:	Cis-Amminedichloro (2-Methylpyridine) Platinum Platinum, Amminedichloro(2-methylpyridine)-, (SP-4-3)

picoplatin

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