piperazinedione
A crystalline antibiotic fermentation product isolated from the bacterium Streptomyces griseoluteus with antineoplastic activity. Piperazinedione alkylates DNA at the N-7 position of guanine, inhibiting DNA replication and inducing cell cycle arrest.
| Synonym: | compound 593A Merck Compound 593A; |
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| Abbreviation: | PZD |
| Code name: | 593A |
| IND number: | 10158 |
| NSC code: | 135758 |