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piperazinedione

A crystalline antibiotic fermentation product isolated from the bacterium Streptomyces griseoluteus with antineoplastic activity. Piperazinedione alkylates DNA at the N-7 position of guanine, inhibiting DNA replication and inducing cell cycle arrest.

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Synonym:	compound 593A Merck Compound 593A;
Abbreviation:	PZD
Code name:	593A
IND number:	10158
NSC code:	135758

piperazinedione

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