recombinant interferon gamma
A recombinant therapeutic agent which is chemically identical to or similar to the endogenous lymphokine interferon gamma (IFN-gamma) with antineoplastic, immunoregulatory, and antiviral activities. Therapeutic IFN-gamma binds to and activates the cell-surface IFN-gamma receptor, stimulating antibody-dependent cytotoxicity and enhances natural killer cell attachment to tumor cells. This agent also activates caspases, thereby inducing apoptosis in malignant cells.
Synonym: | gamma interferon |
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Abbreviation: | IFN-G |
IND number: | 1706 1951 2192 2591 4521 |
NSC code: | 373360 600662 635256 |