NCI Drug Dictionary

The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

An orally administered third generation platinum compound with potential antineoplastic activity. Satraplatin forms highly reactive, charged, platinum complexes which bind to nucleophilic groups in DNA, inducing intrastrand and interstrand DNA cross-links, as well as DNA-protein cross-links. These cross-links result in cell growth inhibition and apoptosis. Check for active clinical trials using this agent. (NCI Thesaurus)

US brand name:Orplatna
Code name:BMS-182751
Chemical structure:
  • (OC-6-43)-bis(acetato)amminedichloro(cyclohexylamine)platinum
  • (OC-6-43)-bis(acetato-O)amminedichloro(cyclohexanamine)platinum
  • platinum,bis(acetato-O)amminedichloro(cyclohexanamine)-,(OC-6-43)