siplizumab
A monoclonal immunoglobulin G1 antibody with potential antineoplastic activity. Siplizumab binds to CD2, a specific receptor found in T cells and NK cells, thereby triggering a host immune response that results in lysis of CD2+ cells, selective suppression of the immune system, and control of activated T cell growth.
| Synonym: | anti-CD2 monoclonal antibody |
|---|---|
| Abbreviation: | MEDI-507 |
| Code name: | MEDI-507 |