NCI Drug Dictionary

The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

sivifene gel
The phenylhydrazone 4,4'-dihydroxybenzophenone-2,4-dinitrophenylhydrazone formulated as a topical agent with immunomodulating and potential antineoplastic activities. Applied topically as a gel, sivifene may stimulate a local immune response against human papillomavirus (HPV)-induced cervical intraepithelial neoplasia (CIN). Check for active clinical trials using this agent. (NCI Thesaurus)

Code name:A-007
Chemical structure:
  • 4,4'-[[2-(2,4-dinitrophenyl)hydrazinylidene]methylene]diphenol
  • 4,4'-dihydroxybenzophenone-2,4-dinitrophenylhydrazone
  • methanone, bis(4-hydroxyphenyl)-, (2,4-dinitrophenyl)hydrazone