NCI Drug Dictionary

The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

tyrosinase-related protein-1
A recombinant peptide of the tyrosinase-related protein 1 (TRP1) used in vaccine therapy. Expressed by cells of melanocyte origin, TRP1 is an enzyme involved in the process that converts tyrosinase to melanin pigments. Vaccination with TRP1 may stimulate cytotoxic T cell responses to melanoma cells. Check for active clinical trials using this agent. (NCI Thesaurus)

Synonym:gp75 antigen
tyrosinase related protein-1
tyrosinase-related protein 1