NCI Drug Dictionary

The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

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tyrosinase-related protein-1
A recombinant peptide of the tyrosinase-related protein 1 (TRP1) used in vaccine therapy. Expressed by cells of melanocyte origin, TRP1 is an enzyme involved in the process that converts tyrosinase to melanin pigments. Vaccination with TRP1 may stimulate cytotoxic T cell responses to melanoma cells. Check for active clinical trials using this agent. (NCI Thesaurus)

Synonym:gp75 antigen
tyrosinase related protein-1
tyrosinase-related protein 1
Abbreviation:TRP-1