NCI Drug Dictionary

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The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

imidazole mustard
A synthetic derivative of imidazole with potent antineoplastic properties. Imidazole mustard alkylates DNA, preferentially at guanine residues, resulting in DNA interstrand crosslinks and inhibition of DNA replication and RNA and protein synthesis. Check for active clinical trials using this agent. (NCI Thesaurus)

TIC mustard
Chemical structure:5-[3,3-bis(2-chloroethyl)-1-triazeno]imidazole-4-carboxamide