NCI Drug Dictionary

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The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

iodine I 131 tositumomab
A monoclonal antibody directed against the CD20 protein expressed on the surface of B-lymphocytes and radiolabeled with the radioisotope iodine I 131 with potential antineoplastic activity. Iodine I 131 tositumomab binds to and selectively delivers cyctotoxic radiation to CD20-expressing B-lymphocytes, thereby minimizing systemic radiotoxicity. Check for active clinical trials using this agent. (NCI Thesaurus)

Synonym:131-I-anti-B1 antibody
131-I-anti-B1 monoclonal antibody
iodine I 131 MOAB anti-B1
iodine I 131 monoclonal antibody anti-B1
iodine-131 anti-B1 antibody
iodine-131 anti-CD20 monoclonal antibody